Home Medication What does alat mean in a blood test. What is alt in the blood and what is the norm of this indicator

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What does alat mean in a blood test. What is alt in the blood and what is the norm of this indicator

Alanine aminotransferase and aspartate aminotransferase are endogenous enzymes and are significant markers in biochemical blood tests.

Although an elevated ALT level does not clearly indicate the occurrence of health problems, nevertheless, both enzymes are simply not present in blood in large volumes.

Yes, the level of both ALT and AST can increase with liver disorders (for example, with cirrhosis or hepatitis), but other markers must be carefully analyzed. By the way, the level of AlAT can be increased if myocardial infarction is diagnosed.

Aminotransferases are a group of enzymes that can catalyze transamination reactions, playing a leading role in protein metabolism, as well as maintaining the relationship between protein and carbohydrate metabolism. The most significant natural catalysts for transamination reactions in the human body are alanine aminotransferase (otherwise ALT, ALAT) and aspartate aminotransferase (otherwise AST, AcAT).

These enzymes are present in the tissues of many organs. Normally, aminotransferases are practically not detected in the blood. The minimum activity of enzymes is determined by natural regenerative processes in the body. Increased levels of AlAT and AsAT are highly sensitive markers of damage to the tissues in which they are contained.

The method for determining aminotransferases in a biochemical blood test has been widely used in clinical practice due to its high sensitivity and specificity.

AsAT and AlAT. Norm

Normally, aspartate aminotransferase does not exceed 31 IU / L in women and 37 IU / L in men. In newborns, the indicator should not exceed 70 PIECES / L.

AlAT in women normally does not exceed 35 IU / l, and in men - 40 IU / l.

Also, the results of the analysis can be presented in moles / hour * L (from 0.1 to 0.68 for AlAT and from 0.1 to 0.45 for AsAT).

What may affect transaminase levels

The following can lead to distortion of the analysis results:

the use of certain medications:
- a nicotinic acid,
- immunosuppressants
- choleretics
- hormonal birth control, etc.)
obesity,
pregnancy,
physical inactivity or excessive physical activity.

How is the study

For analysis, blood is taken from a vein. The results of an urgent study provide within 1-2 hours. With standard diagnostics - during the day.

To obtain the most reliable results, you must:

exclude the use of medicines a week before the tests (if this is not possible, it is necessary to notify the doctor about the drugs taken);
donate blood exclusively on an empty stomach;
the day before the study excludes physical activity, smoking, alcohol, fatty and fried foods - two days in advance.

What can the analysis on ALaT and AsAT tell?

Alanine aminotransferase and aspartate aminotransferase are characterized by selective tissue activity. If considered in
in decreasing order the content of these enzymes in organs and tissues, the list will look like this:

alanine aminotransferase: liver, kidney, myocardium, muscles;
aspartate aminotransferase: myocardium, liver, muscles, brain, kidneys.

Almost any malfunction in the human body affects the composition of the blood, so its biochemical analysis serves as the basis for diagnosis. As a result, many patients are interested in AlAT and AsAT. Liver tests for enzymes are the most important method for detecting severe liver diseases.

CONSULTATION ON RESULTS OF ANALYSIS AND ultrasound - 500 rubles. (at the request of the patient)

These substances are representatives of the enzyme group, normally having an insignificant level in the blood. In diseases accompanied by cell destruction, the parameters of these enzymes in the analyzes increase at times or even tens of times, which confirms the presence of a pathological process.

The value of liver enzymes

Transferases — catalysts for the transfer of molecular residues and functional groups from molecule to molecule — serve as a separate enzyme class.

Transferases are involved in the conversion of nucleic and amino acids, lipids and carbohydrates. The most significant liver enzymes are considered indicators of AlAT and AsAT, which perform several tasks at once.

Molecular intracellular synthesis provides sufficient liver functionality.
Enzymodiagnosis carried out by measuring the degree of activity of enzymes in the blood. The reliability of this method is based on the fact that the liver enzymes in a healthy person are contained inside the cell, leaving it only after the death of the cell itself.
The prognostic role of enzymes is associated with the features of their dynamics in the composition of the blood, which directly depends on the nature of the course and severity of the disease.
The medicinal role of enzymes is to use special enzyme preparations when they are deficient in the body.

What is alanine aminotransferase (AlAT)

The functioning of the human body is ensured by multiple chemical processes that are simultaneously cyclical and interconnected, continuous and sequential. Enzymes play a major role in blood filtration and digestion systems. Alanine aminotransferase (AlAT) is the main liver enzyme involved in the metabolism of amino acids. Most of the enzyme is in the liver, a small amount in the kidneys, cardiac and skeletal muscles.

Alanine itself is important as a source of fast glucose production for brain and central nervous system nutrition. A study of the level of AlAT and AsAT in the blood greatly facilitates the diagnosis and prognosis of severe diseases and injuries of the liver, heart and pancreas.

The specificity of AlAT allows us to differentiate diseases according to the degree of exceeding standard values, which is very important for mild symptoms, similarity of manifestations of various diseases. Using ALAT indicators in combination with other tests, the doctor can determine the degree of organ damage and make a prognosis of the course of the disease.

What is the AlAT test done for?

The endogenous enzyme AlAT serves as a reliable marker of liver tests - liver pathologies in diagnostic laboratory practice. Alanine aminotransferase is formed due to intracellular synthesis, therefore, it is present in blood in small doses.

Blood test for maintenanceAlAT in a healthy person shows a minimum value. Diseases or damage to the liver cause the death of its cells, while the intracellular liver enzyme AlAT is released into the bloodstream, which, along with other indicators, is a rather informative indicator of painful processes. Any deviations of the enzyme indicator from the normative range, especially upward, are an indisputable sign of a beginning liver disease or an extensive process of its destruction

An increased level of ALAT in pregnant women, with a heart attack and certain pathological conditions, can also be observed. An increase in the dose of AlAT in the blood is noted before manifestations of jaundice, which allows for the early diagnosis of liver diseases.

Who is prescribed a test for AlAT

AlAT test is prescribed in the presence of certain symptoms and factors:

Symptoms of liver disease:

weakness, lack of appetite, nausea and vomiting;
abdominal pain, jaundice;
dark urine and clarified feces.

Risk factors for liver disease:

previous hepatitis
alcohol addiction,
diabetes and obesity,
hereditary causes
taking drugs that aggressively affect the liver.

AlAT blood test is performed for the following purposes:

checking for possible liver damage due to injuries;
identification of drug and alcohol dependence in the framework of a set of interrelated indicators;
assessment of the effects of anticholesterol therapy and a number of other drugs that are relatively toxic to the liver;
elucidation of the cause of jaundice in the patient - liver disease or impaired blood function.

The patient to whom the AlAT test is prescribed should inform his doctor about the presence of reasons that can reduce the accuracy of the analysis results:

taking certain medications, dietary supplements and herbal infusions (oral contraceptives and aspirin, warfarin and paracetamol, infusions of valerian and echinacea);
possible pregnancy;
the presence of allergies;
passing a course of intramuscular injections;
rehabilitation period after cardiac surgery or cardiac catheterization;
active physical activity before the test.

The test is based on the patient’s venous blood, results can be ready in about 12 hours.

AlAT enhancement levels

The standard indicator of AlAT as part of the diagnostic complex " "May vary slightly in different laboratories, but on average the boundaries of this indicator for men are 10–40 U / L, for women - from 7 to 35 U / L. The criteria for the differentiation of diseases are the levels of exceeding the norm of AlAT:

Minor:

taking medications and chemicals (antibiotics and barbiturates, chemotherapy and drugs),
cirrhosis of the liver,
fatty liver damage;

Moderate and medium:

alcohol poisoning
some forms of hepatitis
growth problems in adolescents;

High:

cancer necrosis,
viral hepatitis,
state of shock.

How Hepatitis Alanine Aminotransferase Levels Depend on Sex

Russian scientists, having examined 320 people, among whom were both sick people and healthy people (control group), found that in women with CVH, ALaT in 78.6% of cases did not correspond to the severity of the disease. Some patients even reported normal levels.alanine aminotransferase.

In men, the number of cases of hepatitis is not accompanied by excess concentration of this enzyme was only 21.4%, that is, the difference between the sexes is 3.7 times. Moreover, even with approximately the same severity of the disease, in women thisindicator was 1.5 times lower.

The female body has great potential for combating liver pathology, therefore, if a representative of the weaker sex has obvious signs of the presence of “liver problems”, then one analysis Alanine aminotransferase is not enough - it may not be informative. At a minimum, you still have to go through.

In order to get a real picture of the liver, you need to conduct other liver tests, then you can more accurately say whether a woman has this pathology or not. Representatives of the fair sex are much more likely to have a latent course of CVH, when symptoms of liver damage appear later, in the presence of pronounced, sometimes irreversible, changes. In addition, they are characterized by a more rapid restoration of the normal ALaT level after Botkin's disease, which is also associated with the physiological characteristics of the female body.

All these factors must be taken into account when examining men and women for the presence of liver pathologies.

Sex dependence of alanine aminotransferase levels in viral hepatitis

Norma ALaTwith various types of hepatitis, it can increase by 20 or even 100 times. Moreover, the cause of this pathology (viruses, poisoning, erythrocyte hemolysis) does not play a role.

With Botkin's Disease an increase in this biochemical parameter can be observed even before the appearance of jaundice and other clinical symptoms. Alsothe norm of ALaT in the blood can be increased some more time after recovery, returning to normal(women - 31 units / liter; men - 45 units / liter) in two to three weeks.
With "syringe" viral hepatitis, especially those with chronic and protracted course (CVH), this indicator can constantly fluctuate in a smaller or larger direction. Sometimes it depends on the stage of the infectious process, and in some cases such jumps are difficult to explain.
Obstructive jaundice also causes abrupt changes in the concentration of ALaT. With this pathologylevelalanine aminotransferase in the blood can rise up to 600 IU / l per day, and then, spontaneously return to normal somewhere in two days.

If obstructive jaundice arose due to primary liver cancer, the concentration of alanine aminotransferase remains stably high.

Features of the norms of AlAT in pregnant women

In a healthy woman, AlAT, the norm during pregnancy does not change and should coincide with the values \u200b\u200bbefore conception. In cases where AlAT is elevated slightly during pregnancy, causes that are not associated with diseases can be considered:

intramuscular injection;
excessive exercise for a pregnant woman
addiction to fast food;
uncontrolled intake of dietary supplements;
obesity;
fetal pressure on the biliary tract, preventing the outflow of bile.

Normalization of nutrition, moderate physical activity, weight control and choleretic drugs normalize enzyme parameters.

The dependence of the level of AlAT on age and other indicators

Over the course of a person’s life, ALaT levels change. You need to know this in order to correctly decipher ALaT in a biochemical blood test.

In healthy full-term newborns, the norm of alanine aminotransferase is from 10 to 17 U / L.
If the baby was born prematurely, this figure can be 13–26 U / L, and the level of this substance in the blood of such babies changes almost daily.
From the sixth day of life to six months of age, the upper limit of the alanine aminotransferase index slightly increases and amounts to 30 U / L. This is due to the fact that in the first six months in the baby’s body, all biochemical mechanisms are gradually “triggered”, because the child adapts to existence outside the mother’s womb.
From seven months to a year, this indicator ranges from 13–29 U / L. At this time, the indicators for boys and girls are not yet different.
From year to 14 years, the concentration of alanine aminotransferase in boys and girls is different. Moreover, in the female body it will be lower than in the male. In girls of preschool age, the concentration of 13–18 U / L will be considered the norm, and in boys, the upper limit is already 22 U / L. This trend will continue throughout life.

Adult Alanine Aminotransferase Levels

Before reaching the age of 60, the norm of alanine aminotransferase in men is 10–45 U / L, while ALaT is normal in women in this period only 10–31 U / L.
The level of this substance in the blood can change only during pregnancy, and then not all women. In some cases, it remains unchanged. If the future mother has a slightly increased ALaT level and amounts to 35 U / L, this is not a cause for concern. An increase in ALaT during pregnancy is caused by the fact that an enlarged uterus can squeeze the bile ducts slightly or a slight bend in the biliary tract appears. It is not necessary to be afraid of this state of affairs - after the birth, the uterus will decrease, and the indicators will return to normal. However, if the increase in the increase in ALaT in the blood during pregnancy continues, and the concentration of this substance reaches high numbers, additional examinations should be taken, as this may be associated with a violation of the liver, kidneys and heart.
When people “cross” the 60-year-old barrier, the rate of alanine aminotransferase in the blood also changes. ALaT normally in men of this age is from 10 to 40 units / liter, and for women it will be 10–28 units / liter. At this level, the concentration of alanine aminotransferase remains until the end of life.

However, not always a normal level in the blood of a given substance suggests that a person is healthy. In some cases, even with severe pathologies of the liver and kidneys, the indicator does not change, especially for the fairer sex. That's why isolatedconcentration study this enzyme in the blood is prescribed very rarely. Most often, other biochemical parameters are analyzed in parallel, which allows a much more accurate idea of \u200b\u200bthe state of the body.

What is aspartate aminotransferase (AsAT)

The endogenous enzyme aspartate aminotransferase (AcAT) is responsible for accelerating the release of ammonia from amino acids for its subsequent processing in the urea cycle. AsAT is found not only in the liver, but also in the heart muscle and brain, kidneys and spleen, lungs and pancreas. Due to the intracellular nature of the synthesis, AcAT is successfully used in the diagnosis of the state of the myocardium and liver. Using a biochemical blood test for AsAT and AlAT, as well as their ratio, doctors manage to predict a heart attack even before the appearance of the main symptoms.

AsAT is also used as a marker in the differential diagnosis of a number of diseases:

Cirrhosis and hepatitis;
Liver metastases;
Jaundice of various origin.

If, according to the results of the study, high ALAT values \u200b\u200bare much greater than the excess of the norm for AsAT, this is a characteristic sign of liver damage. If AsAT is increased more than AlAT, a version of myocardial cell death should be considered. Excessive activity of alanine aminotransferase is also possible while taking certain drugs. Possible lower values \u200b\u200bof AcAT and AlAT during pregnancy, renal failure or pyridoxine deficiency.

Where to pass liver tests in St. Petersburg

Any tests, including tests for liver enzymes AlAT and ASaT, you can pass in. The clinic is located in St. Petersburg, near the metro. We guarantee accurate results, sterility and confidentiality.

ALT is an enzyme from the transaminase group whose full name is alanine aminotransferase. Its level is determined by a biochemical blood test. The substance is excreted in all metabolic processes, but in small quantities.

An increase in ALT concentration may indicate damage to internal organs. The largest enzyme reserves in the liver, therefore, it is considered a marker of pathologies of the hepatobiliary system. The enzyme enters the bloodstream during the destruction of parenchymal organs and muscle tissue, which doctors determine by comparing its level and other indicators of biochemistry.

What is ALT and its role in the body

Alanine aminotransferase is a protein substance that is necessary for amino acid metabolism. Together with other similar enzymes, low molecular weight proteins are transported in this way:

ALT is responsible for alanine;
AST (aspartic aminotransferase) - for aspartic acid;
GGTP (gammaglutamyltranspeptidase) - for glutamic acid.

The active part of the enzyme is disconnected by the coenzyme of pyridoxine (vitamin B6). ALT is present in all organs and muscle tissue. Elevated enzyme concentrations are detected in parenchymal structures. The largest amount is found in the liver. In lower concentrations, ALT is determined in tissues:

heart muscle;
pancreas;
kidney
lungs.

A small amount of the substance enters the blood during metabolism. The bulk is in the organs in a bound form. Here's the enzyme:

regulates the metabolic rate;
participates in immunity;
involved in the synthesis of energy;
supports the vital activity of cells.

The release of ALT in large numbers occurs during mass cell death. The more enzyme is released, the more intense the destruction process. Determining the level of ALT refers to liver tests, since it is with damage to this organ that the deviation of enzyme indices is most noticeable.

ALT is an unstable indicator. It depends on age, gender. The amount of the enzyme can vary with hormonal fluctuations, changes in the concentration of vitamins and minerals. The level depends on the characteristics of the human metabolism and other individual factors. Stress, physical activity, drugs, and some aspects of the patient’s lifestyle can affect the value of ALT.

Table - ALT standards in blood by age

Population category	Reference value, U / l
Newborns 1‒2 days	Up to 31
After 3 days of life	Up to 50
1-6 months	Up to 56
6-12 months	Up to 52
1-3 years	Up to 33
3-6 years	Up to 30
6-18 years old	Up to 26
Adult women	Up to 35
Adult men	Up to 40
Pregnant women	Up to 32
Aged people	19‒30

Indications for analysis

Blood tests on ALT are carried out for the purpose of prevention in order to assess the state of the body as a whole, the preservation of the functions of internal organs, the balance of electrolytes and vitamins. The study is appropriate for the early diagnosis of diseases, since it reflects the slightest changes in the basic parameters of the blood and supplements the information obtained from its general analysis. It is prescribed for suspected somatic diseases and functional disorders, the patient's complaints are the cause.

Table - Symptoms in which you need to evaluate ALT

Category	Alarms
Signs of liver disease	Jaundice (icteric sclera, discoloration of the skin and mucous membranes, dark urine, discoloration of feces) Pain in the right hypochondrium Digestive disorders (alternating constipation and diarrhea, flatulence)
General disorders	Sleep disturbances (nightmares, insomnia) Psycho-emotional instability (irritability, tearfulness, apathy, aggression) Lack of appetite Weakness, fatigue
Other	Subfebrile condition Headaches, pressure behind the sternum Dry mucous membranes Fragility of nails and hair Sweating

In addition to heart and liver diseases, damage to the pancreas can be suspected by ALT level. Alcoholics are prone to pancreatitis and pancreatic necrosis, as well as people who regularly eat fatty, fried, smoked foods.

Deviations of biochemical data are observed with extensive injuries (burns, electric shocks, muscle injuries), bone fractures, hematological pathologies. ALT is often elevated after surgery. Physiological prerequisites for the growth of the enzyme level are stresses, loads, carbohydrate diets.

Drugs that increase ALT include oral contraceptives, glucocorticosteroid hormones, chemotherapy drugs, antibiotics and antiviral agents.

Minor and pathological deviations

Assessing the degree of enzyme (the presence of enzymes in the blood) is not considered an accurate measure for diagnosing diseases. Focusing on the analysis data, one can only suspect the presence of pathological processes, as well as their intensity. To draw conclusions correctly, you need to be guided by the norms, permissible deviations, as well as their combinations among themselves.

Since ALT always indicates cell damage, minor violations of reference values \u200b\u200b(2–3 units) are considered physiological. Such changes are not considered a reason for further examination and are simply ignored. If the level of increase is greater, you need to look for its cause. You can suspect it by how much the ALT indicator is changed:

up to 2 times - there may be a mistake during the analysis, violation of the preparation rules, severe stress, overwork, medical procedures on the eve, you need to retake the test;
2–3 times - they suspect the use of alcohol, significant errors in the diet, injuries, excessive physical activity;
3-5 times - such an increase is observed against the background of the use of hepatotoxic drugs, injuries of internal organs, after surgical interventions, burns, and also with chronic pancreatitis;
5 or more times - inflammation of the liver tissue with an infectious lesion can be suspected;
10 times - muscle dystrophy, chronic liver disease, or initial forms of destructive processes are possible;
20 times or more - dangerous liver diseases, cancer progression, cirrhosis.

ALT and other indicators

In order to assess the patient’s condition with maximum accuracy, doctors analyze not only the compliance of each individual indicator with the standards, but also a combination of deviations. In serious diseases, deviations affect most biochemical parameters.

Together with ALT, the significance of another enzyme, AST, is considered. It is also present in the cells of the parenchymal organs, but the bulk is concentrated in the heart muscle.

In healthy people, AST levels are approximately 1.5 times higher than ALT. In the opposite situation, metabolic disorders can be suspected, when proteins are consumed for energy and carbohydrates are stored as reserves.

An important value for diagnosis is the de Ritis index. This is the ratio of AST and ALT. Its norm is 1.33, a deviation of 0.4 units is allowed in the direction of increase or decrease. A significant increase in the index is observed with myocardial damage (more than 2). The index approaches 2 for chronic alcoholic liver damage. Pathologies of the hepatobiliary tract provoke a significant decrease in the rate. In most cases, elevated ALT is accompanied by an increase in bilirubin concentration.

To detect liver diseases, it is important to evaluate several enzymes at once (ALT, AST, alkaline phosphatase, gamma glutamyl transpeptidase) and the degree of their deviations. The larger they are, the more intense the pathological process and the higher the threat to the health and life of the patient.

Table - Enzyme Level Deviation

Mild and moderate disorders are observed in non-alcoholic fatty liver disease, chronic viral hepatitis, as well as in the initial stages of the development of tumor diseases. An average increase accompanies chronic inflammatory lesions of the gland, ethanol poisoning. A significant increase in indicators is observed in the acute form of hepatitis, toxic damage, as well as in the late stages of cancer or cirrhosis.

Why is ALT elevated during pregnancy?

During the bearing of a child, the female body undergoes total changes. First of all, metamorphoses affect the hormonal background. The concentration of bioactive substances is constantly growing up to childbirth. An increase in the uterus and the baby is accompanied by pressure on the internal organs. All of them suffer from increased loads associated with the need to supply the fetus with nutrients, utilize its metabolic products, and increase blood volume.

The normal ALT level for pregnant women should be below 32 U / L. The indicator rises slightly in the first and third trimester. Moderate changes are considered a variant of the norm. If a woman did not suffer from heart or liver diseases before conception, does not complain of poor health, treatment is not required. The growth of indices by more than 1.5 times requires increased attention. This may be a signal for the development of gestosis, eclampsia, diseases of the cardiovascular system, liver or gall bladder. Often this happens against the background of prolonged use of a gestagenic medicine - Dufaston, Utrozhestan, Susten.

ALT in children

The concentration of alanine aminotransferase is increased in children of the first year of life. This is due to the active development of organs and systems, adaptive mechanisms that are aimed at adapting to life outside the mother’s womb. The second peak falls on the puberty. At this time, the child grows rapidly, the formation of a hormonal background. When development slows down, ALT levels decrease and remain stable. If enzyme levels are greatly increased, this indicates dangerous diseases (as in adults).

What to do with elevated ALT

In most cases, doctors recommend retaking the test (in case of errors in the blood test or violation of the preparation rules). An additional examination is prescribed only if significant deviations are detected repeatedly. Often it includes a general analysis of blood and urine, ultrasound of the liver and other internal organs, MRI or CT, tests for tumor markers.

Different laboratories use different equipment for analysis, use different units of measurement. In this case, a high indicator can be perceived by the patient himself as a deviation, when in fact it is not there. In addition, ALT needs to be evaluated along with other values. Without special knowledge, it is difficult to correctly understand the results.

With deviations in the results of blood biochemistry, you should consult a doctor. The child should be shown to the pediatrician, pregnant women should make an appointment with their obstetrician-gynecologist, and adults with the doctor who ordered the examination or therapist. It is better not to draw independent conclusions, but to entrust the reading of the research protocol to a specialist.

In addition to the analysis itself, it is important to collect a family history, interview the patient for complaints, and conduct a physical examination to detect objective symptoms of the pathology. All this will help narrow the circle of searches for the disease that caused the increase in ALT.

How to be treated

ALT level is a laboratory indicator, a sign of destruction of cells of parenchymal organs. Enzyme elevation itself cannot be treated. Therapy is fully aimed at the underlying disease, which provoked a shift in the result outside the normal range. It is important to stop the destructive processes and start the regeneration of the organ (if possible). With irreversible changes, the goal of treatment is to slow down the destruction and provide surgical assistance (liver transplantation, for example).

The list of medications depends entirely on the nature of the disease (for infections prescribe antiviral or antibiotics, for oncopathologies chemotherapy). The treatment regimen is selected, focusing on the patient's condition. With a significant excess of ALT, the patient is observed in a hospital (hepatitis, cirrhosis, cholestasis). Small deviations that do not pose a threat to the patient's life can be eliminated on an outpatient basis.

The main group of drugs that are used when the enzyme indicators deviate from the norm are hepatoprotectors. Means of this group have antioxidant, anti-inflammatory properties. They improve the functioning and start the restoration of hepatocytes, optimize the synthesis and properties of bile, preventing its stagnation in the ducts.

Most of the hepatoprotectors have anti-inflammatory properties. The predominant amount of these drugs have similar indications. Some of them are used in the complex therapy of hepatitis, hepatosis and cirrhosis, and part - for violations of the biliary tract, accompanied by cholestasis (cholelithiasis, cholelithiasis).

Table - Best hepatoprotectors

FAQ

Question: Do I need a diet with elevated ALT?

Answer: Diet therapy is an indispensable aspect of the comprehensive treatment of any liver pathology. Its task is to reduce the load on the gland, ensure a normal outflow of bile and optimize metabolic processes. A therapeutic diet is recommended even for small deviations in children and pregnant women, so as not to aggravate liver damage. You need to adjust the diet in the case when you need to be treated with drugs that are dangerous to the body (antiviral drugs or powerful antibiotics). In most cases, doctors recommend sticking to the Pevzner 5 diet (for diseases of the liver, bile, pancreas).

Question: The dietary table menu is so complicated ... Can you somehow briefly characterize the general principles of nutrition at high enzymes?

Answer: Everything harmful is excluded from the diet - fatty, fried, smoked, flour, sweets, canned food, marinades and pickles, fast food, soda and alcohol. The menu should include all types of cereals (except barley), easily digestible proteins (chicken, fish, turkey, dairy products), lots of vegetables and fruits (in any form). It is important to replace animal fats with vegetable oils of cold pressed (fill them with cereals and salads), enter nuts in the menu. You need to eat fractionally, in small portions, every 3 hours to optimize the secretion of bile. Drinking regimen should be observed (1.5 liters of water per day, except for other liquids).

Question: Is it possible to lower the indicator by folk methods (without drugs and diets)?

Answer: As part of the complex therapy of liver pathologies, you can use herbal remedies (decoctions and infusions). For example, liver collection, Hepatophyte tea, milk thistle meal. The people recommend brewing corn stigmas, dandelion root, yarrow, St. John's wort, peppermint. All these methods can be auxiliary or used to prevent stagnation of bile. In the treatment of serious diseases alone herbs can not do. Moreover, phytotherapy and vitamins with the development of oncopathologies can only do much harm. Before using any alternative prescription, it is better to consult your doctor.

Question: Can a high ALT be a false result?

Answer: Maybe. An error should be suspected if only this indicator is increased or deviations are insignificant (up to 2 times). That is why biochemistry often has to be retaken. In order to reinsurance, you should properly prepare for the test:

exclude alcohol and drugs a week before blood donation;
limit junk food in 3 days;
eliminate stress, overstrain and physical activity on the eve of the analysis;
donate blood only in the morning, on an empty stomach.

Even if all conditions are met, and the result shows deviations, it is better to analyze again. This eliminates the senseless going to the doctors and the cost of hardware diagnostic methods.

Question: What are the symptoms that indicate that ALT is elevated and it’s time to take a biochemical blood test?

Answer: An increase in the level of enzymes in the blood does not cause specific symptoms. According to clinical signs, one can only assume the presence of a disease that can provoke abnormalities of ALT from the norm, for example:

damage to the pancreas is accompanied by girdle pain in the abdomen, nausea, vomiting, flatulence, stool disorders, fever;
liver pathologies are manifested by pain under the right rib, jaundice, periodic disorders in the digestive tract, general disorders of the state;
heart disease can be suspected by pressing and stitching pains in the chest (often radiating to the arm, scapula, collarbone), shortness of breath, swelling, cyanosis of the limbs.

conclusions

ALT is an important laboratory feature that helps evaluate the health of internal organs. The average norm for adults and schoolchildren is 35 units / liter. Deviations mainly indicate diseases of the liver, heart, pancreas and indirectly can talk about the pathology of the kidneys and lungs. With an increase in ALT, hepatic impairment, or rather cell destruction, is primarily suspected. In order to accurately establish the problem, ALT is considered in combination with bilirubin and other enzymes. A complete diagnosis can be made by comparing the results of biochemistry, a general analysis of blood and urine, ultrasound of the internal organs. It is not necessary to treat high ALT, but a disease that caused its growth.

Along with ALT, another enzyme is always considered - A FROMT (aspartate aminotransferase). In women, it should be up to 31 units / liter, in men up to 41 units / liter. An increase in the concentration of AST in the blood indicates the destruction of the cells of the heart, liver, pancreas and other organs.

Alanine aminotransferase (ALT) is a special substance involved in amino acid metabolism. It is usually found in organs such as the liver, heart, and kidneys.

The penetration of this enzyme into the bloodstream is evidence of the presence of a pathological process. What this means and what ailments are associated with will be described later in the article.

In most cases, alanine aminotransferase is elevated in diseases affecting the liver. However, the possibility of pathology and other vital organs is not excluded.

The concentration of ALT in the blood is an important diagnostic indicator that determines the location and severity of the pathology.

The main functions of ALT

This enzyme is important for health. Thanks to it, metabolic processes are carried out, which helps to strengthen the immune system, provide the body with the necessary energy reserve, as well as the production of lymphocytes.

All processes occur inside the cells with a small release of the enzyme into the bloodstream.

Due to the destructive process that occurs in the cells of the liver and other organs affected by the disease, ALT penetrates into the blood in large quantities. Its presence, exceeding the permissible values, becomes an important indicator for the diagnosis of certain diseases.

The presence of alanine aminotransferase is characteristic of such organs as:

the liver, where its concentration is the highest;
heart muscle;
lungs;
kidneys
pancreas.

This becomes a prerequisite for a thorough examination of precisely these organs when high levels of ALT are detected in a blood biochemical analysis.

Indications for analysis

An increase in ALT in a blood test signals not only pathology in these organs. It also indicates the possibility of other diseases.

That is why blood biochemistry is evaluated. The analysis reveals deviations, it becomes an integral part of preventive measures, an effective way to diagnose serious diseases of the liver, myocardium and pancreas.

This study becomes mandatory when observing pathological changes in the liver that occur as a result of taking medications, hepatitis and poisoning with toxic substances.

A biochemical blood test is prescribed in case of the following symptoms:

intense pain in the right hypochondrium;
yellowness of the skin and eye sclera;
lightening feces and dark urine;
lack of appetite;
general weakness.

Other symptoms

In addition to the manifestations listed above, indicating a high level of ALT in the blood, there are symptoms that manifest depending on the lesion of a particular organ:

Liver. Ailments are accompanied by painful manifestations under the right ribs, a change in the color of the skin and yellowness of the eyes. Viral hepatitis occurs against a background of elevated body temperature. Cirrhosis is characterized by the accumulation of fluid in the abdominal cavity, the so-called spider veins appear on the skin.
Heart. The main symptom of myocardial infarction is intense pain in the chest area, extending to the subscapular zone, left arm and jaw. The heart rhythm is broken, shortness of breath occurs, the pressure decreases. General weakness, chills.
Pancreas. Nausea, recurring vomiting, sharp or aching pain in the stomach, bloating, weakness.

If there is an oncological process, in addition to these signs, there is a sharp weight loss and loss of strength.

Diagnostics

Identification of a high level of enzymes in combination with the listed manifestations makes it possible to quickly diagnose diseases, which significantly increases the effectiveness of treatment.

For research, blood from a vein is taken in the morning on an empty stomach. The reliability of the results depends on the preliminary preparation of the patient with the implementation of simple rules:

the last meal no later than 8 hours before sampling the biomaterial;
alcohol exclusion and smoking cessation;
limitation of physical activity.

In the case of the use of drugs should inform the doctor.

Only if these requirements are met, will the analyzes be accurate, which will make it possible to make an accurate diagnosis.

Decryption analysis

It should be noted that when decoding the results, the values \u200b\u200bof an enzyme such as AST are still taken into account. According to the Ritis coefficient scale, which considers the ratio of these enzymes, indicators up to 1.65 conventional units are taken as the norm.

Exceeding these values \u200b\u200bby 2 times indicates pathological changes in the heart muscle. Values \u200b\u200bbelow 1.0 indicate liver damage.

However, with hepatitis of viral origin, a decrease in these values \u200b\u200bis observed, and liver damage due to alcohol poisoning provokes a significant increase.

A comprehensive examination of a patient with a high level of enzymes involves the use of MRI, CT, a general analysis of urine and blood, and a number of other measures.

Norms ALT

In adults and in children, there is a significant difference in the indicators, which are considered within the normal range. The table shows that the permissible concentration of this substance depends not only on age, but also on gender:

The indicated values \u200b\u200bare approximate, but fluctuations up or down are allowed small - from 1 to 3 units.

Factors affecting performance

The reasons for the increase in ALT are quite diverse. But most often they indicate a pathology of the liver and are a kind of marker of its condition. In addition, high values \u200b\u200bare found even with minor diseases of other organs, when they are accompanied by cell destruction.

Among them:

Varieties of hepatitis. In this case, the chronic and viral forms do not cause a significant deviation of ALT from the norm.
Obstructive jaundice. High rates are also observed extremely rarely.
Cirrhosis of the liver. It is characterized by the absence of pronounced symptoms for a long time.
Fatty liver disease - steatosis. This condition is characterized by a slight increase in blood count. However, if the pathology turns into steatohepatitis, alanine aminotransferase significantly increases, and the level of direct and total bilirubin also increases.
Malignant neoplasms in the liver. Often become a consequence of hepatitis. Biochemical analysis to determine ALT indices allows not only diagnosing the disease, but also concluding that surgical intervention is necessary. ALT values \u200b\u200bincrease significantly after chemotherapy.
Pancreatitis With an exacerbation of the inflammatory process in the pancreas, ALT increases. Indicators can increase 3-6 times.
Myocarditis (damage to the heart muscle). In addition to increasing the level of the enzyme, shortness of breath becomes a striking symptom.
Myocardial infarction. The pathology is indicated by the excess of ALT values \u200b\u200bby 5 times. An increase of 10-12 times indicates the progression of deterioration.
Alcoholism. There is an increased concentration of ALT, increasing after drinking.
Muscular dystrophy. ALT values \u200b\u200bcan increase by 8–9 times.

Extremely high rates provokes acute hepatitis: excess of the norm by 20-45 times.

Other reasons

In addition to diseases, physiological causes also act as factors causing a deviation of ALT values \u200b\u200bto a greater extent. Among them:

excess of permissible physical activity;
drinking alcohol before the examination;
stressful situations;
the use of fatty, fried, spicy foods.

Increased rates are noted during pregnancy. A slight deviation is considered natural.

Uncontrolled medication significantly affects the results of the analysis. Therefore, whenever possible, one should refrain from using them before carrying out the analysis.

How to bring indicators back to normal

The exceptional informativeness of the results of blood biochemistry on ALT, which makes it possible to diagnose a wide range of pathological conditions, does not give reason to independently draw conclusions and make decisions.

This prerogative should be given to qualified doctors..

The fundamental principle in an integrated approach to eliminating the problem is further examination to determine the root cause of the deviation from the norm. After finding out which disease served as a trigger for increasing the values, the doctor will choose the right treatment tactics.

Diseases characterized by a particularly severe clinical course suggest a treatment course in a hospital setting.

These include:

pancreatic necrosis;
extensive myocardial infarction;
acute and infectious hepatitis;
cirrhosis of the liver;
oncology.

The treatment of each of them is specific and requires strict adherence to the recommendations of the doctor.

Drug treatment

Among the most effective drugs used specifically to lower enzymes in the blood, hepatoprotectors should be noted:

Essential H;
Heptral;
Karsil;
Tykveol.

Drugs in this group prevent further destruction of liver cells and other organs. At the same time, they restore cells damaged by the pathological process.

Other measures

In addition to taking hepatoprotectors, choleretic drugs and drugs that improve digestive processes, it is recommended to adhere to a diet:

food should be fractional and frequent;
fatty, fried and spicy foods should be excluded from the diet;
banned smoked meats;
it is not recommended to use marinades, to get involved in pickles;
food should be steamed, baked, simmered or boiled;
limit the use of strong tea, coffee;
exclude alcohol and smoking.

On the use of folk methods

As auxiliary agents, the use of decoctions and infusions from chamomile, thyme, St. John's wort, peppermint is allowed.

However, you should consult your doctor before using them.

Self-medication and an irresponsible attitude to one’s health are the most harmful.

In order to avoid serious consequences caused by untimely contacting a specialist, a blood test should be done 1-2 times a year. This will not miss the onset of the devastating effects on the body of diseases of the liver, pancreas and heart.

When cells are destroyed as a result of damage to an organ, ALT enters the bloodstream, which is an important diagnostic indicator.

What is alanine aminotransferase necessary for and where is it contained

Alanine aminotransferase in the body plays an important role by participating in the metabolism of amino acids, in particular the essential amino acid alanine. He, in turn, plays a role in providing energy to the central nervous system, strengthening immunity, regulating metabolism and producing lymphocytes.

Where ALT is Contained:

ALT analysis, delivery rules and norms

ALT is included in the biochemical analysis of blood along with other transaminases. It is necessary to take the analysis on an empty stomach, in the morning. Exclude alcohol in a week. At least eight hours should pass after dinner. All this is important for obtaining reliable data. Taking certain drugs affects the ALT rate, which is why when taking oral contraceptives, aspirin, paracetamol, warfarin, be sure to inform your doctor about this.

A blood test is taken from a vein

Reasons for increasing ALT

An increase in ALT in the blood occurs as a result of cell destruction. What diseases lead to this?

Hepatitis is an acute or chronic inflammatory process in the liver of an infectious or nutritional toxic nature. Viral hepatitis develops when infected with hepatitis viruses (A, B, C, D, E and F). Moreover, the disease can be asymptomatic for a long time. For example, viral hepatitis C is therefore called a “gentle killer,” since for a long time, damaging liver cells, it does not manifest itself. Ultimately, cirrhosis develops. Alimentary toxic hepatitis develops under the influence of substances that destroy liver cells. In particular, long-term alcohol consumption leads to it.

This is the effect of large doses of alcohol on the liver.

Liver cirrhosis is the outcome of all liver damage, when the destroyed cells are replaced by connective tissue, and it can no longer perform its functions. All this leads to liver failure and serious complications.

It is worth noting that, in addition to ALT, acute hepatitis is accompanied by an increase in other transaminases (AST, GGTP), and the level of bilirubin also increases.

Pancreatitis - damage to the pancreas with necrosis of its tissue. The reasons for the development are the abuse of fatty foods and alcohol or stones in the biliary tract. Patients with a chronic form of pancreatitis need to check this indicator throughout their lives to prevent exacerbation.

The predominant increase in ALT over AST will be with liver damage, and if on the contrary - with the heart.

Myocarditis is an inflammatory disease of the heart, characterized by damage to the heart muscle. In this situation, a blood test also has a high concentration of ALT and AST.

Burns, frostbite, multiple organ failure, extensive injuries - all these conditions are accompanied by a significant increase in ALT.

Also, oncological processes in the above organs are the reasons when ALT is elevated.

When ALT is lowered

A reduced ALT content is possible with a deficiency of folic acid and certain vitamins. With cirrhosis of the liver, a decrease in ALT is a poor prognostic sign, indicating the complete absence of preserved healthy cells.

Pregnancy

During pregnancy, in the first trimester, a slight increase in ALT is possible. There is nothing terrible in this, it is physiological and is associated with the pregnancy itself. If ALT increases significantly, and characteristic symptoms appear, it is urgent to consult a doctor for examination.

Symptoms

Symptoms of increased alanine transaminase in the blood are diverse. The clinical picture is due to the affected organ and the disease that led to this.

From the liver

A characteristic symptom of cirrhosis is the “jellyfish head”, a combination of ascites and varicose veins of the abdominal wall

With liver damage, pain in the right hypochondrium, nausea, vomiting are possible. Possible yellowness of the skin, icteric sclera. With viral etiology, there may be hyperthermia. With developed cirrhosis, rashes appear on the body like vascular asterisks, an increase in the abdomen due to ascites (accumulation of fluid in the abdomen).

Varicose veins (esophagus, stomach), which may be complicated by bleeding. Gradually, multiple organ failure develops.

From the pancreas

Pancreatitis is manifested by severe pains in the abdomen, in the navel, its bloating, repeated vomiting, weakness, and subsequent clouding of consciousness.

From the heart

The main symptom of myocardial infarction is a pronounced, burning pain behind the sternum, which can spread to the left arm, jaw, under the shoulder blade

A painless form of a heart attack is possible, or atypical, when the pain is localized in the abdomen, or severe shortness of breath develops. In addition to pain, a possible violation of the heart rhythm, a drop in blood pressure. Concerned expressed weakness, fear of death, chills.

In the presence of an oncological process in the affected organ, strong weight loss in a short period of time, weakness, and increased fatigue are possible.

Diagnostics

Diagnosis of the disease, the causes of increased ALT, is carried out by doctors using all available research methods. In many cases, on an emergency basis, since among them there are diseases that threaten life and lead to disability.

A correctly interpreted biochemical blood test can lead to the right diagnostic path. So, there is the concept of the de Retis index, which is the ratio of increased AST and ALT. Its norm is 0.91-1.75.

If it exceeds two, then the cause is in the heart muscle. If less than one, then the liver is affected.

In the hospital, a full examination is carried out, including in addition an MRI or CT scan, advanced blood and urine tests. Invasive methods are also used, such as puncture biopsy and angiography of the blood vessels of the heart. All this allows you to quickly make the correct diagnosis and begin treatment.

Treatment

In order to reduce ALT, it is necessary to cure the disease that led to this, after which the ALT norm will return on its own.

An approximate set of products for patients with diseases of the liver and pancreas

Severe diseases such as pancreatic necrosis, extensive myocardial infarction, severe hepatitis, complicated by multiple organ failure, are treated in the intensive care unit.

The treatment of each disease is specific and it does not make sense to paint it. A few words can be advised to people taking drugs that affect the liver, as well as alcohol abusers. In such cases, it will be useful to periodically drink a course of hepatoprotectors (carlsil, essentials) and at least somehow protect the liver cells from damage, thereby lowering ALT.

With many diseases, such as pancreatitis, hepatitis, diet is very important. Reduce consumption or completely eliminate all fatty, spicy, smoked, salty and alcohol. To prevent exacerbations, a healthy lifestyle should be your goal in itself!

Hello! Can two out of three hepatitis vaccines give a positive hepatitis B test? ALT-23, AST-50. Thanks for the answer.

I have alt 180, what does that mean?

And I have AST 1566 and ALT 1555. Viral hepatitis was ruled out, I don’t drink alcohol, I go in for sports, I lead a healthy lifestyle, there are no gallstones.

Good afternoon! I have ALT 134, what does this mean and what examinations should be done? AST is OK

Good afternoon! I have Ast-63.71 Alt-82.57, abdominal ultrasound is normal, MRI is normal, pain in the right hypochondrium, doctors cannot deliver anything, what kind of examinations need to be passed !? Thanks for the answer!

I have AST 38.4, Alt-46.9, vaccinated against hepatitis B in 2011. I don’t drink, don’t smoke, I go in for sports. What is it?

Good afternoon, I have A-ALT-42 U / L, A-AST-32U / L, what could it be? What examination should I do?

Good afternoon, I have a blood chemistry analysis: A-ALT- 42 U / L, A-AST-32 U / L, what does this mean? Tell me what kind of examination do I need to do?

I have AST-39.9, ALT-59.7, total bilirubin 12.4. What could it be, how should I be examined? Answer please.

Good afternoon! I have ALT-45.8; AST-34.8; Bilirubin - 9.8. I lead a healthy lifestyle, but I use ROSISTARK statin (rosuvastatin), 0.5 ml every day. Due to this, total cholesterol is 4.92 (when I do not use this drug, cholesterol rises to 7). What should I do, please advise. Ultrasound found nothing special in the liver. Maybe you need to get a statin, for example. in Switzerland (there is such an opportunity), maybe there is a more “pure” drug? Without statins, cholesterol rises again, especially since there was already a microstroke.

alt-46.6, ast-28.1. What could be?

This is a slight increase, most likely, the liver was overloaded, monitor the diet, after 2 weeks do the analysis again.

On the 2nd day after the operation to remove the gallbladder, a blood test was taken, ALT and AST were more than 150, bilirubin was 0.03 higher (the drainage had not yet been removed, because there was a little fluid, ultrasound showed). The hospital said that the tests were almost normal, and the gastroenterologist said that I had almost hepatitis (tests were normal before the operation), all organs were not inflamed. Is the doctor right? What could it be from?

Good afternoon. I have Alat 50 and Asat 24.2, cholesterol 7.95 and triglycerides 3.79. With cholesterol it is clear, and what are the remaining indicators talking about? Thanks.

Elevated levels of ALT in the blood - the main causes

ALT - alanine aminotransferase. It is a specific enzyme involved in the production and breakdown of proteins. It is synthesized by cells of various organs: liver, spleen, kidneys, lungs, heart muscles. Normally, a small amount enters the bloodstream. A blood ALT test is a common diagnostic test.

Diagnosis based on ALT analysis

The detection of alanine aminotransferase levels is carried out as part of a general biochemical blood test. Complaints in which a blood test for ALT is prescribed are:

Fatigue;
Decreased appetite;
The occurrence of weakness in the body;
Pain on the right side of the abdomen;
Discoloration of urine;
Yellowness of the skin;
Pain in the heart;
Desires to nausea.

Possible diseases with increased ALT

It is mandatory to detect aminotransferase levels in patients with obesity, diabetes mellitus, and liver diseases.

Important! Blood donation is performed in the morning on an empty stomach. It is not recommended to drink alcohol and fatty foods the day before the analysis.

It is also worth refraining from taking potent medicines. The psycho-emotional state of a person and physical stress can affect the results of the study.

Exceeding the Threshold

In medical research, the upper threshold of ALT is important. The limit for adult males is 45 u / l, for women 34 u / l. An increase in ALT in a blood test indicates an inflammatory process in the body. The following are the diseases that cause such a pathology.

Pancreatitis Severe damage to the pancreas. It occurs due to the appearance of a tumor that blocks the enzyme ducts. As a result, the accumulated digestive enzymes begin to digest the pancreas itself. Lethal outcome possible;
Hepatitis. Liver disease. It is characterized by inflammation of the tissues of the organ. It is subdivided into several types. The most dangerous is hepatitis C. The latter often goes into a chronic form, and can cause cirrhosis. Common causes of hepatitis are: toxic damage to liver cells (eg, alcohol), viral infection;
Myocardial infarction. The most severe heart disease. It is characterized by the death of some parts of the heart muscle, due to a critical decrease in blood circulation. The pathology has many causes. Basic: smoking, hypertension, obesity, diabetes mellitus, sedentary lifestyle.

There are reasons for exceeding the ALT norm in a blood test that are not related to the listed diseases:

Chemotherapy;
Injuries accompanied by damage to the muscles of the body;
Taking potent drugs
Physical and emotional stress;
Eating fatty fried foods
The use of drugs.

Important! The main recommendations aimed at reducing the likelihood of these diseases will be: proper nutrition, refusal to use narcotic drugs (including alcohol, nicotine), moderate exercise, and reduction of stressful situations in life.

De Rittis coefficient

One of the most important research methods is considered to be a comparison of the ALT level with the level of AST - aspartate aminotransferase. The latter is also an endogenous enzyme involved in the synthesis of amino acids. Aminotransferases have similar threshold levels in the blood. The diagnosis of one or another pathology depends on the balance of ALT and AST. The AST / ALT ratio is characterized by a de Rittis coefficient.

Important! The normal value of the de Rittis coefficient is 1.33-1.75 u / L.

A decrease in the norm below 1 unit / liter will mean a viral damage to the liver. An increase in the coefficient to 2 u / l and higher, provided that the albumin content is high, indicates myocardial infarction.

Normal ALT / AST in the body:

Alalninaminotransferase: men - up to 45 units / l, women - up to 34 units / l;
Aspartate aminotransferase: men - up to 41 units / l, women - up to 31 units / l.

Self-decryption of analyzes

Often, patients, having read medical information, try to independently decipher the blood test for ALT level. Having received the results in the laboratory, some people, seeing the deviation of the indicators from normal values, independently diagnose serious diseases in themselves.

Doctors know that exceeding ALT thresholds is not always a sign of pathology. Results from different laboratories may vary. It depends on the equipment, on the research methods, on the materials used in the analysis. Other factors can also influence the results, be it the patient’s improper lifestyle, medication, emotional state, and others.

Correctly decipher the results of studies can only be a doctor. He prescribes medication.

To date, doctors do not use ALT analysis as a means of accurate diagnosis. Exceeding ALT in a blood test indicates only the possibility of a disease. For the final diagnosis, additional studies are used, specialists of a narrow profile are involved: urologists, cardiologists and others.

Normalization of ALT level with folk remedies

After the examination, medication is prescribed to a patient with a high ALT level. But for prevention, the doctor can recommend herbal medicine. Below are examples of the use of folk remedies to reduce the level of alanine aminotransferase.

Thistle broth. To prepare a teaspoon of chopped herbs, pour a glass of boiling water, wrap and let it brew for 20 minutes. Then filter the infusion. Take a decoction in small sips, half an hour before meals, twice a day, for three weeks;
Herbal harvest. The immortelle, St. John's wort and celandine are mixed. The proportion of herbs is, respectively. The collection is poured with 1 liter of hot water, wrapped and infused for 12 hours. Then you need to strain the infusion. Take half a cup 4 times a day, for two weeks;
Infusion of dandelions. For cooking, take 200 grams of crushed dandelion flowers. Pour 100 ml of vodka. The drug is insisted during the day. Take 2 tablespoons three times a day, for three weeks;
Decoction of corn stigmas. To prepare the product, take dried crushed stigmas. Pour 200 ml of boiling water and insist a minute. Take the infusion twice a day in a glass. The course of treatment can be six months.

Important! Folk remedies are not a cure! They are used for the prevention of diseases and general strengthening of the body.

The level of development of modern medicine allows you to accurately diagnose most known diseases. One of the generally accepted research methods is a biochemical blood test. It contains many indicators, one of which is the level of alanine aminotransferase.

Exceeding the normal level of ALT indicates the possibility of developing serious diseases in the body. But only a doctor can accurately determine the ailment. We strongly recommend not to engage in self-diagnosis and especially self-medication. If disturbing symptoms occur, consult a clinic immediately. They will carry out all the necessary examinations and help you deal with the problem.

How to get rid of varicose veins

The World Health Organization has officially announced varicose veins as one of the most dangerous mass diseases of the day. According to statistics over the past 20 years - 57% of patients with varicose veins die in the first 7 years after the disease, 29% of them in the first 3.5 years. The causes of death vary - from thrombophlebitis to trophic ulcers and the cancerous tumors caused by them.

About how to save your life if you were diagnosed with varicose veins, the head of the Phlebology Research Institute and academician of the Russian Academy of Medical Sciences told in an interview. See the full interview here.

Attention

In the near future we will publish information.

Increased ALT in the blood: causes and treatment

Alanine aminotransferase (ALT) is a special substance involved in amino acid metabolism. It is usually found in organs such as the liver, heart, and kidneys.

In most cases, alanine aminotransferase is elevated in diseases affecting the liver. However, the possibility of pathology and other vital organs is not excluded.

The concentration of ALT in the blood is an important diagnostic indicator that determines the location and severity of the pathology.

The main functions of ALT

All processes occur inside the cells with a small release of the enzyme into the bloodstream.

The presence of alanine aminotransferase is characteristic of such organs as:

the liver, where its concentration is the highest;
heart muscle;
lungs;
kidneys
pancreas.

This becomes a prerequisite for a thorough examination of precisely these organs when high levels of ALT are detected in a blood biochemical analysis.

Indications for analysis

An increase in the level of ALT in the blood signals not only about the pathology in these organs. It also indicates the possibility of other diseases.

That is why blood biochemistry is evaluated. The analysis reveals deviations, it becomes an integral part of preventive measures, an effective way to diagnose serious diseases of the liver, myocardium and pancreas.

This study becomes mandatory when observing pathological changes in the liver that occur as a result of taking medications, hepatitis and poisoning with toxic substances.

A biochemical blood test is prescribed in case of the following symptoms:

intense pain in the right hypochondrium;
yellowness of the skin and eye sclera;
lightening feces and dark urine;
lack of appetite;
general weakness.

Timely detection of elevated ALT levels makes it possible to eliminate such signs by making an accurate diagnosis and prescribing an adequate course of treatment.